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Saturday, August 1, 2020 | History

3 edition of Bioassay of Arcolor 1254 for possible carcinogenicity. found in the catalog.

Bioassay of Arcolor 1254 for possible carcinogenicity.

National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

Bioassay of Arcolor 1254 for possible carcinogenicity.

by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

  • 90 Want to read
  • 17 Currently reading

Published by Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Cancer Institute, Division of Cancer Cause and Prevention in Bethesda, Md .
Written in English

    Subjects:
  • Carcinogens.,
  • Polychlorinated biphenyls -- Toxicology.

  • Edition Notes

    SeriesCarcinogenesis technical report series ; no. 38, DHEW publication ; no. (NIH) 78-838, DHEW publication -- no. (NIH) 78-838.
    The Physical Object
    Paginationx, 62 p. :
    Number of Pages62
    ID Numbers
    Open LibraryOL15219731M

    An overview of Genetic Toxicology Micronucleus study conclusions related to Aroclor (). PCBs and Human Health. Aroclor The critical study identified was a study of rhesus monkeys conducted by Dr. Arnold and others in The monkeys were exposed to varying doses of PCBs ingested in gelatin capsules for a period of five years. NIH National Toxicology Program Bioassay of Aroclor® for Possible Carcinogenicity.

      National Cancer Institute (NCI). Bioassay of Aroclor for possible carcinogenicity. NCI-GC-TR Bethesda, MD: National Cancer Institute. NTIS PB Norback DH and Weltman RH. Polychlorinated biphenyl induction of hepatocellular carcinoma in the Sprague-Dawley rat. Environ Health Perspect Prasad UK. . Purchase Bioassays - 1st Edition. Print Book & E-Book. ISBN ,

    µg/mL in MeOHSingle Component. @article{osti_, title = {Effects of Aroclor reg sign on hydrocortisone levels in adult Rhesus monkeys (Macaca mulatta)}, author = {Loo, J C.K. and Tryphonas, H and Jordan, N and Brien, R and Karpinski, K R and Arnold, D L}, abstractNote = {Researchers, using female Sprague Dawley rats, reported the effects of chronic ( months) oral dosing with Aroclor {reg .


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Bioassay of Arcolor 1254 for possible carcinogenicity by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention. Download PDF EPUB FB2

A bioassay of Aroclor® for possible carcinogenicity was conducted by administering the test chemical in feed to Fischer rats.

Groups of 24 rats of each sex were administered Aroclor® at one of three doses, eit 50, or ppm, for weeks. Matched controls consisted of groups of 24 untreated rats of each sex.

Bioassay of Aroclor® for possible carcinogenicity (OCoLC) Material Type: Government publication, National government publication: Document Type: Book: All Authors / Contributors: National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

OCLC Number: Notes: "CAS no. " Description. A bioassay of Afoclor* for possible carcinogenicity was conducted by administering the test chemical in feed to^flacher rata.

groups of 24 rats of each sex were administered Aroclor® at 6ne of three doses, either50, or ppm, for weeks. Watched controls consisted of groups of 24 untreated rats of each sex.

Bioassay of Aroclor® for possible carcinogenicity (OCoLC) Material Type: Document, Government publication, National government publication, Internet resource: Document Type: Internet Resource, Computer File: All Authors / Contributors: National Cancer Institute (U.S.).

Division of Cancer Cause and Prevention. POLYCHLORINATED BIPHENYL (AROCLOR ) Consensus Reports. Consensus of polychlorinated biphenyl (aroclor ): NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2A IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man.

7,p. (World Health Organization, Internation Agency for. rinated biphenyls (Aroclor ). Journal of the National Cancer Bioassay of Arcolor 1254 for possible carcinogenicity. book ; 53 (2): ― 7) National Toxicology Program. Bioassay of aroclor for possible carcinogenicity.

National Cancer Institute Car-cinogenesis Technical Report Series ; 1― 8) Kimbrough RD, Squire RA, Linder RE, et al. Induction. National Cancer Institute, Bioassay of Aroclor for Possible Carcinogenicity, CAS #2 73 2 3NTIS Springfield, VA PB-2 79 62 4/1 GA NCI-CG TR DHEW/Pub.

Purchase Bioassay - 1st Edition. Print Book & E-Book. ISBNBook Edition: 1. Veröffentlicht in der Reihe Gesundheitsschädliche Arbeitsstoffe, Lieferung, Ausgabe Der Artikel enthält folgende Kapitel. IARC (I) International Agency for Research on Cancer (World Health Organization) 1 The agent (mixture) is carcinogenic to humans.

2A The agent (mixture) is probably carcinogenic to humans; there is limited evidence of carcinogenicity in humans and sufficient evidence of carcinogenicity in experimental animals. Of the few such longterm studies of the toxicity of PCBs currently available, three long-term studies are discussed in detail below: (a) the National Cancer Institute's bioassay of Aroclor for possible carcinogenicity in male and female Fischer rats, (b) the study of Kimbrough et al.

() on the induction of liver tumors in Sherman Cited by: 2. We designed the current study to compare the effects of two lots of Aroclor (lots and ). We analyzed these two lots for PCB congeners, polychlorinated dibenzofurans (PCDFs), polychlorinated naphthalenes (PCNs), and polychlorinated dibenzodioxins (PCDDs).Cited by:   A bioassay of Aroclor® for possible carcinogenicity was conducted by administering the test chemical in feed to Fischer rats.

Groups of 24 rats of each sex were administered Aroclor® at one of three doses, eit 50, or ppm, for weeks.

Matched controls consisted of groups of 24 untreated rats of each sex. Aroclor was admin to each rat 7, 28, and 49 days after the DENA, and some rats were killed 21 days after each dose of Aroclor. Liver of rats that received Aroclor on either day 7 or on day 28 contained in increased level of gamma-glutamyltranspeptidase.

FUNDAMENTAL AND APPLIED TOXICOLOGY 4, () Chronic Toxicity and Oncogenicity Bioassay of Inhaled Ethylene in Fischer Rats' THOMAS E. HAMM, JR.,Z DEREK GUEST,3 AND JOHN G. DENT 4 Chemical Industry Institute of Toxicology, BoxResearch Triangle Park, North Carolina Chronic Toxicity and Oncogenicity Bioassay of Cited by: Aroclor was fed to groups of 24 male and 24 female F rats, from 7 weeks of age, at dietary concentrations of 25, 50 and ppm for up to weeks.

There was a dose- related depression of body weight gain for both sexes and decrease in survival for male : J M Ward. An assessment of the chronic toxicity and oncogenicity of Aroclor, Aroclor, Aroclor, and Aroclor administered in diet to rats, Volume I.

Schenectady, NY: Environmental Research Center, General Electric. Batelle Cited by: Male and female F rats were fed a diet containing 0, 25, 50, or ppm Aroclor® for 26 months. Rats fed 50 or ppm Aroclor® had a lower body weight than the control animals and developed signs of PCB toxicity.

The incidence of stomach lesions increased as the dietary intake of Aroclor® increased. Author(s): Stanford Research Institute.; National Institutes of Health (U.S.); Carcinogenesis Testing Program (U.S.) Title(s): Bioassay of aroclor for.

Oncologists from the HERD Oncology Branch reviewed the NCI report "Bioassay of Aroclor for Possible Carcinogenicity" and extracted the detailed tumor data presented in' TabLe 9.

Categories for leukemias, malignant lymphomas, liver carcinomas, stomach adenocarcinoma and gastrointestinal tract malignancies, and all malignant tumors combined.

Induction of liver tumors in Sherman strainfemale rats by polychlorinated biphenyl Aroclor J NatI Cancer Inst(). (). Institute. Bioassay of Aroclor for Possible Carcinogenicity. Carcinogenesis (). Issues in RiskAssessment. ().Author: V J Cogliano.Aroclor for approximately 22 months showed no evidence of overt toxicity.

Effects occurring in the offspring of these monkeys consisted of hairline hyperpigmentation at greater than or equal to mg/kg-day, and decreased birth weight and possible File Size: KB.Bioassay of Aroclor" for possible carcinogenicity. NCI Carcinogenesis Technical Report Series Num NCI-CG-TR, DHEW Publication No.

(NIH) (cited in USAF ). NIOSH (National Institute for Occupational Safety and Health).